In 2000, Christopher Nolan's striking thriller Memento captivated audiences with its innovative portrait of a man disoriented by short term memory loss, hunting for his wife's killer. In a cinematic landscape littered with scientific myths, Memento is noteworthy for its authentic, but no less intriguing, dramatization of neurological disorder. As we revisit this intellectually challenging film on its 10th anniversary, we celebrate Nolan's unconventional storytelling—as exciting now as it was then.

After the Movie: Join us for a conversation featuring special guests from science and screen, including Memento stars Guy Pearce and Joe Pantoliano, screenwriter Jonathan Nolan (whose short story "Memento Mori" inspired the film), New School professor of psychology Dr. William Hirst, and MIT professor of behavioral neuroscience Dr. Suzanne Corkin. Panelists will explore the science of memory as it relates to Memento and more broadly, the history of Hollywood's portrayal of memory as a dramatic theme. Moderated by NPR's Robert Krulwich.